Study Summary
This is a single-arm, open-label, dose-escalation clinical trial designed to evaluate the safety, tolerability, expansion, and persistence of ALPP CAR-T cells in patients with ALPP-positive recurrent or metastatic solid tumors who have progressed after prior therapies. The primary objective is to determine the maximum tolerated dose (MTD), with a secondary aim to assess preliminary clinical efficacy in solid tumors.
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Request More InfoInterventions
Anti ALPP CAR-T cells treatmentBIOLOGICAL
anti ALPP CAR-T cells Treatment follows a lymphodepletion Drug: Fludarabine and Cyclophosphamide.
Study Locations
| Facility | City | State | Country |
|---|---|---|---|
| The Jinling Hospital | Nanjing | Jiangsu | China |