NCT07101549

A Single-center, Single-arm, Dose-escalation Exploratory Clinical Trial on the Safety, Efficacy, and Pharmacokinetics of R-Star001 Cell Injection in Patients With Nectin-4-positive Advanced Solid Tumors

Study Summary

A single-center, single-arm, dose-escalation exploratory clinical trial on the safety, efficacy, and pharmacokinetics of R-Star001 cell injection in patients with Nectin-4-positive advanced solid tumors.

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Interventions

R-Star001DRUG
Drug: Nectin-4-targeted CAR T-cell injection with inducing IL-18 secretion (R-Star001). The trial consists of a traditional '3 + 3' pattern dose-escalation phase and a dose-expansion phase.

Study Locations

FacilityCityStateCountry
Cancer Hospital Chinese Academy Of Medical Sciences,Shenzhen CenterShenzhenGuangdongChina

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: April 14, 2026