NCT06762431

Phase I/II Open-label Study Evaluating The Safety And Efficacy of Concomitant Administration of Anti-CD19 CAR T-cell Therapy and Lenalidomide in Refractory/Relapsed Chronic Lymphocytic Leukemia Patients.

Study Summary

This is a Phase I/II interventional, open-label treatment study designed to evaluate the safety and efficacy of concomitant therapy with anti-CD19 CAR T-cells and Lenalidomide in adult patients with relapsed/refractory chronic lymphocytic leukemia (CLL) who have been pretreated with Ibrutinib for 3 months prior to leukapheresis.

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Interventions

LenalidomideDRUG
Lenalidomide 10mg per os 0- 6 days
LenalidomideDRUG
Lenalidomide 10 mg per os 1 -14 days
Obinutuzumab Injection [Gazyva]BIOLOGICAL
Combined with Lenalidomide 10 mg per os 1- 14 days for 6 cycles

Study Locations

FacilityCityStateCountry
Hematology/Oncology departmentVitebskSelect A StateBelarus

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: August 28, 2026