NCT06561425

A Phase I/II, Multicenter Study Evaluating the Feasibility, Safety, and Efficacy of Point-of-care Manufactured GLPG5101 (19CP02) in Subjects With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

Study Summary

This study is evaluating whether an experimental treatment called GLPG5101 helps to treat non-Hodgkin lymphoma (NHL) and if it is safe to use. This study will be carried out in 2 phases: * The first phase is to see which doses of GLPG5101 work best with the least number of side effects. * In the second phase, participants will receive the selected dose(s) based on the results in the first phase.

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Interventions

GLPG5101GENETIC
Autologous anti-CD19 chimeric antigen receptor (CAR) T cell therapy

Study Locations

FacilityCityStateCountry
Tufts Medical CenterBostonMassachusettsUnited States
Beth Israel Deaconess Medical CenterBostonMassachusettsUnited States
Antwerp University HospitalEdegemBelgium
UZ LeuvenLeuvenBelgium
CHU De LiègeLiègeBelgium
Algemeen Ziekenhuis DeltaRoeselareBelgium
Cliniques Universitaires Saint-LucWoluwe-Saint-LambertBelgium
Helsingin Yliopistollinen Sairaala (HUS)HelsinkiFinland
Academisch Medisch Centrum (Amsterdam UMC)AmsterdamNetherlands
Leiden University Medical CenterLeidenNetherlands
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)RotterdamNetherlands

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: July 14, 2026