NCT06561425

A Phase I/II, Multicenter Study Evaluating the Feasibility, Safety, and Efficacy of Point-of-care Manufactured GLPG5101 (19CP02) in Subjects With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

Study Summary

This study is evaluating whether an experimental treatment called GLPG5101 helps to treat non-Hodgkin lymphoma (NHL) and if it is safe to use. This study will be carried out in 2 phases: * The first phase is to see which doses of GLPG5101 work best with the least number of side effects. * In the second phase, participants will receive the selected dose(s) based on the results in the first phase.

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Interventions

GLPG5101GENETIC
Autologous anti-CD19 chimeric antigen receptor (CAR) T cell therapy

Study Locations

FacilityCityStateCountry
Tufts Medical CenterBostonMassachusettsUnited States
Beth Israel Deaconess Medical CenterBostonMassachusettsUnited States
Dana-Farber Cancer InstituteBostonMassachusettsUnited States
Antwerp University HospitalEdegemBelgium
UZ LeuvenLeuvenBelgium
CHU De LiègeLiègeBelgium
Cliniques Universitaires Saint-LucWoluwe-Saint-LambertBelgium
Academisch Medisch CentrumAmsterdamNetherlands
Leiden University Medical CenterLeidenNetherlands
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)RotterdamNetherlands

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: April 14, 2026