NCT06280378

A Phase I/II Clinical Study Evaluating the Safety and Efficacy of KL003 Cell Injection in Transfusion-dependent Β-thalassemia

Study Summary

This is a non-randomized, open label, single-dose study in up to 41 participants with β-thalassemia major. The goal of this clinical trial is to evaluate the safety and efficacy of KL003 cell injection in subjects with β-thalassemia major.

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Interventions

KL003 Cell Injection Drug ProductDRUG
Administered by intravenous infusion after myeloablative conditioning with busulfan.

Study Locations

FacilityCityStateCountry
Ruijin Hospital, Shanghai Jiaotong University School of MedicineShanghaiShanghai MunicipalityChina
Institute of Hematology & Blood Diseases HospitalTianjinTianjin MunicipalityChina

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: April 14, 2026