NCT06010875

A Phase I Clinical Study to Assess the Safety and Efficacy of CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Solid Tumors

Study Summary

This is a single-center, double-arm, open-label study. this study plans to evaluate the safety and efficacy of CD70-targeting CAR-T cells in the treatment of CD70-positive advanced/metastatic solid tumors, and obtain recommended doses and infusion patterns.

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Interventions

CD70 CAR-T cellsBIOLOGICAL
After lymphodepletion with Fludarabine and Cyclophosphamide,CAR T cells were transfused intravenically
CD70 CAR-T cellsBIOLOGICAL
After lymphodepletion with Fludarabine and Cyclophosphamide,CAR T cells were injected intraperitoneally

Study Locations

FacilityCityStateCountry
The First Affiliated Hospital of Nanchang UniversityNanchangJiangxiChina

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: April 14, 2026