Liver Biopsy Following Gene Therapy For Hemophilia

Study Summary

This observational study will obtain liver biopsy samples and evaluate the long-term effect of adeno-associated virus (AAV)-mediated gene therapy on the liver tissue in adult patients with hemophilia A or hemophilia B who have previously been treated with a factor VIII or factor IX gene-containing AAV-vector for liver-targeted gene transfer. Participants are from a cohort of patients treated with AAV-mediated gene transfer and at least 6 months after vector infusion.

Interventions

Study Locations

Facility	City	State	Country
St. Jude Children's Research Hospital	Memphis	Tennessee	United States

Official Trial Information

View on ClinicalTrials.gov