NCT05909059

Lymphodepleting Chemotherapy With Fludarabine and Cyclophosphamide Prior to Infusion of CAR T Cell Therapy in Patients With Moderate-Severe Renal Dysfunction

Study Summary

This is a prospective, descriptive study designed to assess the feasibility of administering CAR T therapy among patients with moderate to severe renal impairment using dose adjusted lymphodepleting chemotherapy.

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Interventions

FludarabineDRUG
Received IV on Days -5 to -3 before CAR T cell therapy
CyclophosphamideDRUG
Received IV on Days -5 to -3 before CAR T cell therapy

Study Locations

FacilityCityStateCountry
Caitlin GuzowskiAtlantaGeorgiaUnited States

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: April 14, 2026