NCT05870917

A Prospective, Single-center, Phase II Study of VRD-based Regimen Combined With CART-ASCT-CART2 Treatment in Patients With Newly Diagosed Primary Plasma Cell Leukemia

Study Summary

This is a single-arm, open-label study to evaluate the efficacy and safety of VRD-based Regimen (Bortezomib, Lenalidomide and Dexamethasone) combined with CART-ASCT-CART2 in Chinese patients with newly diagnosed primary plasma cell leukemia.

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Interventions

anti-BCMA CAR-TBIOLOGICAL
Autologous BCMA-directed CAR-T cells, the double infusion intravenously at a target dose of (2-4)±20% x 10\^6 anti-BCMA CAR+T cells/kg respectively

Study Locations

FacilityCityStateCountry
Institute of Hematology and Blood Diseases Hospital Chinese Academy of Medical SciencesTianjinChina

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: April 14, 2026