NCT05223686

A Phase I Clinical Study To Evaluate the Safety and Tolerability of Human CD19-CD22 Targeted T Cells Injection for In Subjects With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia.

Study Summary

To evaluate the safety and tolerability of Human CD19-CD22 Targeted T Cells Injection for the treatment of Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia. Patients will be given a conditioning chemotherapy regimen of fludarabine and cyclophosphamide followed by a single infusion of CD19-CD22 CAR+ T cells.

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Interventions

Human CD19-CD22 Targeted T Cells InjectionDRUG
One time single predetermined dose level CAR-positive T cells will be utilized based on the NMPA approved product label.

Study Locations

FacilityCityStateCountry
Ruijin Hospital, Shanghai Jiao Tong University School of MedicineShanghaiShanghai MunicipalityChina

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: April 14, 2026