NCT04640909

Impact of Treatment With Targeted Therapies on the Generation of Effective CAR T Cells in Patients With Chronic Lymphocytic Leukemia

Study Summary

In this biological study, blood samples will be collected from patients with CLL treated with targeted agents (ibrutinib and venetoclax) to assess the impact of these treatments on the generation of CAR T cells in terms of manufacturing efficiency, immunophenotypic characteristics and functional properties.

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Interventions

Peripheral blood samples withdrawalOTHER
Peripheral blood samples evaluation

Study Locations

FacilityCityStateCountry
Irccs Ospedale S. Raffaele - Milano - Unità Neoplasie Linfocitarie BMilanItaly
Aou Città Della Salute E Della Scienza, Ospedale S. Giovanni Battista Molinette - Torino - Sc Ematologia - Università Degli Studi Di TorinoTorinoItaly

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: April 14, 2026