NCT04581473

An Open, Multicenter, Phase Ib/II Study to Evaluate the Efficacy, Safety and Pharmacokinetics of CT041 Autologous CAR T-cell Injection in Patients With Advanced Gastric/ Gastroesophageal Junction Adenocarcinoma and Pancreatic Cancer

Study Summary

An open, multicenter, phase Ib/II study to evaluate the efficacy, safety and pharmacokinetics of CT041 autologous CAR T-cell injection in patients with advanced gastric/ gastroesophageal junction adenocarcinoma and pancreatic cancer

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Interventions

CT041 autologous CAR T-cell injectionDRUG
Up to 3 times CT041 autologous CAR T-cell injection infusion
Physician's Choice(Paclitaxel or Irinotecan or Apatinib or Anti-PD-1 antibody)DRUG
Physician's choice of any BSC listed above

Study Locations

FacilityCityStateCountry
Anhui Provincial Cancer HospitalHefeiAnhuiChina
Beijing Cancer HospitalBeijingBeijing MunicipalityChina
Fujian Medical University Union HospitalFuzhouFujianChina
Peking University Shenzhen HospitalShenzhenGuangzhouChina
Harbin medical university Affiliated Cancer HospitalHarbinHeilongjiaChina
Henan Tumor HospitalZhengzhouHenanChina
The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenanChina
Tongji Hospital, Tongji Medical College, Huazhong University of Science & TechnologyWuhanHubeiChina
Nanjing Drum Tower HospitalNanjingJiangsuChina
The Second Affiliated Hospital of Soochow UniversitySuzhouJiangsuChina
Northern Jiangsu People's HospitalYangzhouJiangsuChina
The Second Affiliated Hospital of Nanchang UniversityNanchangJiangxiChina
The First Hospital of Jilin UniversityChangchunJilinChina
The First Hospital of China Medical UniversityShenyangLiaoningChina
Shandong Cancer HospitalJinanShandongChina
The Affiliated Hospital of Qingdao UniversityQingdaoShandongChina
Ruijin Hospital, affiliated to Shanghai Jiaotong University, school of medicineShanghaiShanghai MunicipalityChina
Fudan University Shanghai Cancer CenterShanghaiShanghai MunicipalityChina
Shanghai Zhongshan HospitalShanghaiShanghai MunicipalityChina
Sichuan Cancer HospitalChengduSichuanChina
West China Hospital, Sichuan UniversityChengduSichuanChina
Tianjin Medical University Cancer Institute and HospitalTianjinTianjin MunicipalityChina
The First Affiliated Hospital, Zhejiang University School of MedicineHangzhouZhejiangChina
Sir Run Run Shaw Hospital, Zhejiang University School of MedicineHanzhouZhejiangChina

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: April 14, 2026