NCT04010877

Multi-center Phase I/II Clinical Trial of Multiple CAR T Cells for Treating Acute Myeloid Leukemia

Study Summary

The purpose of this clinical trial is to assess the feasibility, safety and efficacy of multiple CAR T-cell therapy which combines CAR T cells against CLL-1 with CAR T cells targeting CD123 or CD33 in patients with relapsed and refractory AML. The study also aims to learn more about the function of CAR T cells and their persistency in AML patients.

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Interventions

CLL-1, CD33 and/or CD123-specific CAR gene-engineered T cellsBIOLOGICAL
Infusion of CLL-1, CD33 and/or CD123-specific CAR-T cells

Study Locations

FacilityCityStateCountry
Shenzhen Geno-immune Medical InstituteShenzhenGuangdongChina

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: April 14, 2026