Study Summary
To evaluate the safety and efficacy of CD19/CD22 Bispecific chimeric antigen receptor (CAR)-T for the treatment of measurable residual disaese (MRD)-positive B cell acute lymphoblastic leukemia. Patients will be given a conditioning chemotherapy regimen of fludarabine and cyclophosphamide followed by a single infusion of CD19/CD22 CAR+ T cells.
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Request More InfoInterventions
anti-CD19/CD22 CAR-T cellsBIOLOGICAL
Retroviral vector-transduced autologous T cells to express anti-CD19 and anti-CD22 CARs
FludarabineDRUG
30mg/m2/d
CyclophosphamideDRUG
300mg/m2/d
Study Locations
| Facility | City | State | Country |
|---|---|---|---|
| Shanghai General Hospital | Shanghai | Shanghai Municipality | China |