NCT03222674

Multi-center Phase I/II Clinical Trial of Multi-CAR T Cell Therapy for Acute Myeloid Leukemia

Study Summary

The purpose of this clinical trial is to assess the feasibility, safety and efficacy of multi-CAR T cell therapy targeting different AML surface antigens in patients with relapsed or refractory acute myeloid leukemia (AML). Another goal of the study is to learn more about the function of the multi-CAR T cells and their persistency in the patients.

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Interventions

Muc1/CLL1/CD33/CD38/CD56/CD123-specific gene-engineered T cellsBIOLOGICAL
Infusion of Muc1/CLL1/CD33/CD38/CD56/CD123-specific gene-engineered T cells

Study Locations

FacilityCityStateCountry
Zhujiang Hospital of Southern Medical UniversityGuangzhouGuangdongChina
Shenzhen Geno-immune Medical InstituteShenzhenGuangdongChina
Yunnan Cancer Hospital & The Third Affiliated Hospital of Kunming Medical University & Yunnan Cancer CenterKunmingYunnanChina

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: April 14, 2026