NCT03064269

CAR-T Therapy for Central Nervous System B-cell Acute Lymphocytic Leukemia

Study Summary

This study will evaluates the safety and efficacy of Chimeric antigen receptor T cells (CAR-T) in treating central nervous system B-cell acute lymphocytic leukemia.

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Interventions

CD19 CAR-T cellsBIOLOGICAL
CNS leukemia is defined as unequivocal evidence of leukemic blasts in the cerebrospinal fluid by cytology or flow cytometry; cranial palsies or a nonhemorrhagic mass seen in cranial computed tomography or magnetic resonance imaging because of infiltration by leukemia cells

Study Locations

FacilityCityStateCountry
The First Affiliated Hospital of Soochow UniversitySuzhouChina

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: April 14, 2026