NCT02782351

Humanized CAR-T Therapy for Treatment of Recurrent or Refractory B Cell Malignancy by Targeting CD19

Study Summary

The present study evaluates the safety and efficacy of humanized Chimeric antigen receptor T cells (CAR-T) in treating recurrent or refractory B cell malignancy targeting CD19 with a humanized scFv. All participants will receive autologous chimeric antigen receptor engineered T cells.

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Interventions

CAR-TBIOLOGICAL
Patients will be infused with autologous CAR-T infusion in a dose escalating manner.

Study Locations

FacilityCityStateCountry
Huaian First People's HospitalHuai'anJiangsuChina
Affiliated hospital of Xuzhou medical collegeXuzhouJiangsuChina

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: April 14, 2026