NCT02546739

Phase I Study of T Cells Expressing an Anti-CD19 Chimeric Receptor in Children and Young Adults With B Cell Malignancies

Study Summary

This study aims to evaluate the safety, efficacy and duration of response of CD19 Chimeric Antigen Receptor (CAR) redirected autologous T-cells in patients with high risk, relapsed CD19+ haematological malignancies.

Want to learn more about this trial?

Request More Info

Interventions

Anti-CD19-CARBIOLOGICAL
Cells extracted, followed by induction chemotherapy before CD19-CAR infusion (dose escalation.)

Study Locations

FacilityCityStateCountry
Beijing Cancer HospitalBeijingBeijing MunicipalityChina
The First Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdongChina
Hebei Yanda Ludaopei HospitalSanheHebeiChina
First Affiliated Hospital of Henan University of Science and TechnologyLuoyangHenanChina
The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenanChina
Huai'An First People'S HospitalHuaianJiangsuChina
Nanjing Drum Tower HospitalNanjingJiangsuChina
First Hospital of Jilin UniversityChangchunJilinChina
Shanxi Dayi HospitalTaiyuanShanxiChina
Tianjin people's hospitalTianjinTianjin MunicipalityChina
Hangzhou Cancer HospitalHangzhouZhejiangChina
Beijing DOING Biomedical Co., LtdBeijingChina

Official Trial Information

View on ClinicalTrials.gov

Data sourced from ClinicalTrials.gov. Last updated: April 14, 2026