Study Summary
This study has two parts with distinct study objectives and study design. In part A, odronextamab is studied as an intravenous (IV) administration with a dose escalation and a dose expansion phase for B-NHL and CLL. The dose escalation phase for B-NHL and the CLL study are closed at the time of protocol amendment 17. In part B, odronextamab is studied as a subcutaneous (SC) administration with a dose finding and a dose expansion phase for B-NHL.
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Request More InfoInterventions
Odronextamab multiple dose levelsDRUG
Administered by intravenous (IV) infusion
Odronextamab multiple dose levelsDRUG
Administered by subcutaneous (SC) injection
Study Locations
| Facility | City | State | Country |
|---|---|---|---|
| University of California, Irvine | Orange | California | United States |
| Stanford University | Stanford | California | United States |
| H. Lee Moffitt Cancer Center | Tampa | Florida | United States |
| Massachusetts General Hospital | Boston | Massachusetts | United States |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | United States |
| Dana Farber Cancer Institute (Massachusetts General Hospital and Beth Israel) | Boston | Massachusetts | United States |
| Mayo Clinic | Rochester | Minnesota | United States |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | United States |
| Memorial Sloan Kettering Cancer Center | New York | New York | United States |
| Weill Cornell Medical College | New York | New York | United States |
| Centre Henri Becquerel | Rouen | Haute-Normandie | France |
| CHU Hôpital Lyon Sud | Lyon | France | |
| Institut Gustave Roussy | Villejuif | Île-de-France Region | France |
| Universitatsklinikum Wurzburg | Würzburg | Bavaria | Germany |
| Meir Medical Center | Kfar Saba | Central District | Israel |
| The Chaim Sheba Medical Center | Tel-Hashomer | Central District | Israel |
| Hadassah Medical Center | Jerusalem | Jerusalem | Israel |
| Assuta Ashdod University Hospital | Ashdod | Southern District | Israel |
| Rambam Health Care Campus - Hematology and Bone Marrow Transplantation Institute | Haifa | Israel | |
| Lady Davis Carmel Medical Center | Haifa | Israel | |
| Royal Cornwall Hospitals NHS Trust | Truro | Cornwall | United Kingdom |
| The Christie NHS Foundation Trust | Manchester | United Kingdom |