Study Summary
This clinical trial studies genetically modified peripheral blood stem cell transplant in treating patients with HIV-associated non-Hodgkin or Hodgkin lymphoma. Giving chemotherapy before a peripheral stem cell transplant stops the growth of cancer cells by stopping them from dividing or killing them. After treatment, stem cells are collected from the patient's blood and stored. More chemotherapy or radiation therapy is then given to prepare the bone marrow for the stem cell transplant. Laboratory-treated stem cells are then returned to the patient to replace the blood-forming cells that were destroyed by the chemotherapy and radiation therapy
Interested in this trial?
Submit an InquiryInterventions
carmustineDRUG
Given IV
cytarabineDRUG
Given IV
melphalanDRUG
Given IV
etoposideDRUG
Given IV
O6-benzylguanineDRUG
Given IV
autologous hematopoietic stem cell transplantationPROCEDURE
Undergo transduced and/or non-transduced transplant
peripheral blood stem cell transplantationPROCEDURE
Undergo transduced and/or non-transduced transplant
laboratory biomarker analysisOTHER
Correlative studies
Study Locations
| Facility | City | State | Country |
|---|---|---|---|
| Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium | Seattle | Washington | United States |